Selank is a synthetic compound modeled after tuftsin, a naturally occurring immune-system compound. It's studied primarily in the context of anxiolytic (anxiety-related) and broader neurological research.
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) that is an analog of the immune peptide tuftsin. It has been studied in rodent research on gene expression in immune tissue and in the brain.
Also known as: TP-7, Selanc, TKPRPGP.
Read more in the Research Library: Selank: a research overview.
For laboratory research use only. Not for human or veterinary use.
Selank has the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). It is built from tuftsin, a four-amino-acid fragment (Thr-Lys-Pro-Arg) of the human immunoglobulin G heavy chain, extended at the C-terminus with Pro-Gly-Pro.
It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Published research includes rodent studies of gene expression in the spleen and in the brain.
Selank has not been evaluated by the U.S. FDA.
Measured the expression of inflammation-related genes in mouse spleen at several time points after Selank and its fragments, and reported changes that varied over time.
Mol Immunol, 2014 PubMedReported that intranasal Selank changed BDNF expression in the rat hippocampus.
Dokl Biol Sci, 2008 PubMedSummaries describe what each cited paper reports in its own model system. They are not claims about the effects of this product.
For laboratory research use only. Not for human or veterinary use.
| Compound | Selank |
|---|---|
| Class | Synthetic heptapeptide, an analog of tuftsin |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP) |
| Molecular formula | C33H57N11O9 |
| Molecular weight | 751.9 g/mol |
| CAS number | 129954-34-3 |
| Form | Lyophilized powder |
| Purity | 99.682% — see the COA for this batch’s full report |
| Amount per vial | 10 mg, 30 mg |
| Batch | SL-502 |
| Certificate of analysis | View the COA (PDF) |