Semax

About Semax

Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) that is an analog of the ACTH(4–10) fragment of adrenocorticotropic hormone. It has been studied in cell-culture and rodent neurochemistry research.

Also known as: MEHFPGP, (Pro8,Gly9,Pro10)ACTH(4–10).

Read more in the Research Library: Semax: a research overview.

For laboratory research use only. Not for human or veterinary use.

Semax research

Background

Semax has the sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP). It is a synthetic analog of the ACTH(4–10) fragment of adrenocorticotropic hormone, modified with a Pro-Gly-Pro tail at the C-terminus.

It was developed in Russia, at the Institute of Molecular Genetics of the Russian Academy of Sciences. Published research includes rodent studies of gene expression and of monoamine systems in the brain.

Semax has not been evaluated by the U.S. FDA.

Selected literature

1. Rat hippocampus

   Reported that Semax, an ACTH(4–10) analog, changed expression of BDNF and its receptor trkB in the rat hippocampus.

   Brain Res, 2006 · publisher page
2. Rodents

   Examined the effects of Semax, an ACTH(4–10) analog, on dopaminergic and serotonergic systems in the rodent brain.

   Neurochem Res, 2005 · publisher page

Summaries describe what each cited paper reports in its own model system. They are not claims about the effects of this product.

For laboratory research use only. Not for human or veterinary use.

Storage & handling

Lyophilized powder

Store the sealed vial at −20 °C (−4 °F), the temperature it ships at.

Light & moisture

Keep the vial sealed and away from light and moisture.

Before opening

Let a sealed vial come to room temperature before opening, to limit condensation inside the vial.

Shipping

Shipped cold-chain.

Batch details

Always follow the label and your batch’s Certificate of Analysis.

Specifications